Characterization of Vomeronasal Receptor Class 2 in Danio rerio: Characterization of V2R genes in Danio rerio

Sabeen  Zahra

doi:10.54393/mjz.v3i02.56

Authors

Sabeen Zahra Department of Pathology, King Edward Medical University, Lahore, Pakistan

DOI:

https://doi.org/10.54393/mjz.v3i02.56

Keywords:

V2R, Danio rerio, Genes, Vomeronasal Receptor Class 2, Zebra Fish

Abstract

The best three distinct families of putative pheromone receptors have been identified in the vomeronasal organ (V1Rs, V2Rs and V3Rs). All are G protein-coupled receptors but are only distantly related to the receptors of the main olfactory system, highlighting their different role. Objective: To characterize the Vomeronasal receptor 2 gene family in Zebra Fish (Danio rerio). Methods: Extensive survey was done to choose top V2R genes. Different software and tools were used to characterize those genes including Eggnog 2.0, MAFFT, ITOL, Weblogo and SOSUI Signal. Results: In order to get insights into this gene family in Zebra fish, we performed an extensive survey of V2R derived datasets. We identified 62 genes distributed among Danio rerio encoding putative vomeronasal proteins. V2R gene family was found to be highly conserved in this study by using Weblogo. It evolved at the level of eukaryotes. The V2R is involved mainly in olfaction. Conclusions: The basic repertoire of V2R genes seems to be larger for most of the species including Danio rerio and gene duplication still plays a role in lineage-specific increases in diversity. V2R gene family is very ancient, has high duplicability suggesting its essentiality.

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